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E-cig vapour doesn't cause an oxidative stress response, but the same can't be said for tradional tobacco.

E-Cig Vapour ‘Doesn’t Cause Oxidative Stress In Viable Lung Epithelial Cells’

Research published in the Chemical Research in Toxicology has shown that, whilst e-cigarettes affect oxidative stress and kill cells, e-cigarette vapour does not. Oxidative stress and cell death can be instrumental factors in causing smoking-related health issues such as COPD and lung cancer. This information echoes previously found information that cigarettes produce a heart cells stress response and e-cig vapours do not. After the same study found that e-cigarettes contain around 95% less toxins than regular tobacco, scientists have looked into the effects of those toxins. Using a vitro model of a lung epithelium, scientists have located the distinction of e-cigs to normal cigarettes. To reach the results, the scientists bubbled the same amount of cigarette smoke and e-cig vapour through a cell-growth medium to create a reserve that could be fused into numerous concentrations. Exposing lung epithelial cells to the vapour and the smoke, the team then utilised a panel of commercially available assays to compare the damage caused. Lung cells that were exposed to cigarette smoke demonstrated signs of oxidative stress and even cytotoxicity, whilst they were unmoved by e-cig vapour. Dr Chris Proctor, a chief scientific officer with British American Tobacco, says that there is evidence e-cigs are safer than regular tobacco. “These data suggest that exposure to vapour from the e-cigarettes tested induces negligible or no oxidative damage to lung epithelial cells at the range of doses tested.” “This highlights the scale of difference in potency between e-cigarette vapour and cigarette smoke and adds to the weight of evidence on the reduced risk potential of e-cigarettes.”
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